Cancer and Brain Genomics (CBG)

Inserm UMR1245 – University of Rouen Normandy

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Publications of team 5

Genetics, Biology & Plasticity of Brain Tumors Team 2021–2026 in chronological order

Patents

FR2311618 —25/10/2023, France (national filing). Castel H*, Mutel A, Bonin M A, Leduc R, Lecointre C, Morin F. Construction comprenant ou constituée d’une séquence peptidique apte à inhiber l’interaction de la filamine A avec le récepteur UT — composition pharmaceutique et produits associés dans le cancer.

WO/2025/087667; PCT/EP2024/077717 — 2025 (international/PCT extension of FR2311618), International (PCT). Castel H*, Mutel A, Bonin M A, Leduc R, Lecointre C, Morin F. Construction comprenant ou constituée d’une séquence peptidique apte à inhiber l’interaction de la filamine A avec le récepteur UT — composition pharmaceutique et produits associés dans le cancer.

Original articles as first/last/corresponding

  1. Chever O, Zerimech S, Scalmani P, Lemaire L, Pizzamiglio L, Loucif A, Ayrault M, Krupa M, Desroches M, Duprat F, Léna I, Cestèle S, Mantegazza M*. Initiation of migraine-related cortical spreading depolarization by hyperactivity of GABAergic neurons and NaV1.1 channels. J Clin Invest. 2021. PMID: 34491914. https://www.jci.org/articles/view/142203
  2. Lorivel T, Cendelin J, Hilber P*. Familiarization effects on the behavioral disinhibition of the cerebellar Lurcher mutant mice: use of the innovative Dual Maze. Behav Brain Res. 2021. PMID: 33091448. https://www.sciencedirect.com/science/article/pii/S0166432820306719?via%3Dihub
  3. Nicola C, Dubois M, Campart C, Al Sagheer T, Desrues L, Schapman D, Galas L, Lange M, Joly F, Castel H*. The Prostate Cancer Therapy Enzalutamide Compared with Abiraterone Acetate/Prednisone Impacts Motivation for Exploration, Spatial Learning and Alters Dopaminergic Transmission in Aged Castrated Mice. Cancers (Basel). 2021 Jul 14;13(14):3518. doi: 10.3390/cancers13143518. PMID: 34298734. https://www.mdpi.com/2072-6694/13/14/3518
  4. Kasapidou PM, de Montullé EL, Dembélé KP, Mutel A, Desrues L, Gubala V, Castel H*. Hyaluronic acid-based hydrogels loaded with chemoattractant and anticancer drug – new formulation for attracting and tackling glioma cells. Soft Matter. 2021 Dec 15;17(48):10846-10861. doi: 10.1039/d1sm01003d. PMID: 34806746. https://pubs.rsc.org/sm/article-abstract/17/48/10846/748454/Hyaluronic-acid-based-hydrogels-loaded-with?redirectedFrom=fulltext
  5. Le Joncour V, Guichet PO, Dembélé KP, Mutel A, Campisi D, Perzo N, Desrues L, Modzelewski R, Couraud PO, Honnorat J, Ferracci FX, Marguet F, Laquerrière A, Vera P, Bohn P, Langlois O, Morin F, Gandolfo P, Castel H*. Targeting the Urotensin II/UT G Protein-Coupled Receptor to Counteract Angiogenesis and Mesenchymal Hypoxia/Necrosis in Glioblastoma. Front Cell Dev Biol. 2021 Apr 14;9:652544. doi: 10.3389/fcell.2021.652544. PMID: 33937253. https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2021.652544/full
  6. Pirlog R, Piton N, Lamy A, Guisier F, Berindan-Neagoe I, Sabourin JC, Marguet F. Morphological and Molecular Characterization of KRAS G12C-Mutated Lung Adenocarcinomas. Cancers (Basel). 2022 Feb 17;14(4):1030. doi: 10.3390/cancers14041030. PMID: 35205778. https://www.mdpi.com/2072-6694/14/4/1030
  7. Lange M, Clarisse B, Leconte A, Dembélé KP, Lequesne J, Nicola C, Dubois M, Derues L, Gidron Y, Castel H, Joly F*. Cognitive assessment in patients treated by immunotherapy: the prospective Cog-Immuno trial. BMC Cancer. 2022 Dec 13;22(1):1308. doi: 10.1186/s12885-022-10384-y. PMID: 36513991. https://link.springer.com/article/10.1186/s12885-022-10384-y
  8. Parment R, Dubois M, Desrues L, Mutel A, Dembélé KP, Belin N, Tron L, Guérin C, Coëffier M, Compère V, Féger C, Joly F, Hilber P, Ribet D, Castel H*. A Panax quinquefolius-Based Preparation Prevents the Impact of 5-FU on Activity/Exploration Behaviors and Not on Cognitive Functions Mitigating Gut Microbiota and Inflammation in Mice. Cancers (Basel). 2022 Sep 10;14(18):4403. doi: 10.3390/cancers14184403. PMID: 36139563. https://www.mdpi.com/2072-6694/14/18/4403
  9. Campisi D, Desrues L, Dembélé KP, Mutel A, Parment R, Gandolfo P, Castel H, Morin F*. The core autophagy protein ATG9A controls dynamics of cell protrusions and directed migration. J Cell Biol. 2022 Mar 7;221(3):e202106014. doi: 10.1083/jcb.202106014. PMID: 35180289. https://rupress.org/jcb/article/221/3/e202106014/213022/The-core-autophagy-protein-ATG9A-controls-dynamics
  10. Fontanilles M, Heisbourg JD, Daban A, Di Fiore F, Pépin LF, Marguet F, Langlois O, Alexandru C, Tennevet I, Ducatez F, Pilon C, Plichet T, Mokbel D, Lesueur C, Bekri S, Tebani A. Metabolic remodeling in glioblastoma: a longitudinal multi-omics study. Acta Neuropathol Commun. 2024 Oct 12;12(1):162. doi: 10.1186/s40478-024-01861-5. PMID: 39394177. https://link.springer.com/article/10.1186/s40478-024-01861-5
  11. Li G, Fan J, Zhang T, Gao T, Chong Y, Liang M, Liang S, Hu B, Yi L, Zhao L, Castel H*. Honeycomb-Inspired Surface-Enhanced Raman Scattering Microarray for Large-Area Automated Testing of Urease in Saliva Samples. ACS Sens. 2024 Apr 26;9(4):2031-2042. doi: 10.1021/acssensors.4c00006. PMID: 38593209. https://pubs.acs.org/ascefj/article/9/4/2031/144315/Honeycomb-Inspired-Surface-Enhanced-Raman
  12. Pedard M, Prevost L, Carpena C, Holleran B, Desrues L, Dubois M, Nicola C, Gruel R, Godefroy D, Deffieux T, Tanter M, Ali C, Leduc R, Prézeau L, Gandolfo P, Morin F, Wurtz O, Bonnard T, Vivien D, Castel H*. The urotensin II receptor triggers an early meningeal response and a delayed macrophage-dependent vasospasm after subarachnoid hemorrhage in male mice. Nat Commun. 2024 Sep 29;15(1):8430. doi: 10.1038/s41467-024-52654-2. PMID: 39341842. https://www.nature.com/articles/s41467-024-52654-2
  13. Seiffert C, Habbeddine N, Grenet M, Martin L, Campisi D, Schapman D, Bénard M, Desrues L, Gandolfo P, Castel H, Morin F*. The autophagy protein ATG9A exerts a non-canonical function in actin-dependent endosomal trafficking. Autophagy. (in revision).
  14. Nicola C, Pedard M, Dubois M, Desrues L, Neveu P, Martin L, Riou G, Johnston I, Dembele KP, Lecras P, Vaudry D, Adriouch S, Joly F, Hilber P, Wurtz O, Castel H*. Differential effects of PD-1 and PD-L1 immune checkpoint inhibition on cognition and anxiety-like behavior through γδT cells and tumor-dependent neuroinflammation. Nat Commun, in review. Preprint posted 2026 Jun 3. doi: 10.21203/rs.3.rs-9519248/v1. (Research Square ‘In Review’, sans PMID à ce jour.)

Original articles in collaboration

  1. Garrido E, Metayer T, Borha A, Langlois O, Curey S, Papagiannaki C, Di Palma C, Emery E, Derrey S, Gaberel T, Gilard V*. Intracranial aneurysms in pediatric population: a two-center audit. Childs Nerv Syst. 2021 Aug;37(8):2567-2575. doi: 10.1007/s00381-021-05151-6. PMID: 33876302. https://link.springer.com/article/10.1007/s00381-021-05151-6
  2. Wilpert NM, Marguet F, Maillard C, Guimiot F, Martinovic J, Drunat S, Attié-Bitach T, Razavi F, Tessier A, Capri Y, Laquerrière A, Bahi-Buisson N*. Human neuropathology confirms projection neuron and interneuron defects and delayed oligodendrocyte production and maturation in FOXG1 syndrome. Eur J Med Genet. 2021 Sep;64(9):104282. doi: 10.1016/j.ejmg.2021.104282. PMID: 34284163. https://www.sciencedirect.com/science/article/pii/S1769721221001488?via%3Dihub
  3. Piton N, Lanic MD, Marguet F, Lamy A, Blanchard F, Guisier F, Viennot M, Salaün M, Thiberville L, Jardin F, Sabourin JC*. An improved assay for detection of theranostic gene translocations and MET exon 14 skipping in thoracic oncology. Lab Invest. 2021 May;101(5):648-660. doi: 10.1038/s41374-021-00536-2. PMID: 33495574. https://www.laboratoryinvestigation.org/article/S0023-6837(22)00643-2/fulltext
  4. Gilard V, Ferey J, Marguet F, Fontanilles M, Ducatez F, Pilon C, Lesueur C, Pereira T, Basset C, Schmitz-Afonso I, Di Fioré F, Laquerrière A, Afonso C, Derrey S, Marret S, Bekri S, Tebani A*. Integrative Metabolomics Reveals Deep Tissue and Systemic Metabolic Remodeling in Glioblastoma. Cancers (Basel). 2021 Oct 14;13(20):5157. doi: 10.3390/cancers13205157. PMID: 34680306. https://www.mdpi.com/2072-6694/13/20/5157
  5. Magne N, Rousseau V, Duarte K, Poëa-Guyon S, Gleize V, Mutel A, Schmitt C, Castel H, Idbaih A, Huillard E, Sanson M, Barnier JV*. PAK3 is a key signature gene of the glioma proneural subtype and affects its proliferation, differentiation and growth. Cell Oncol (Dordr). 2021 Dec;44(6):1257-1271. doi: 10.1007/s13402-021-00635-8. PMID: 34550532. https://link.springer.com/article/10.1007/s13402-021-00635-8
  6. Metayer T, Leclerc A, Borha A, Derrey S, Langlois O, Barbier C, Aldea S, le Guerinel C, Piotin M, Vivien D, Briant AR, Emery E, Gaberel T*. Microsurgical Clipping of Middle Cerebral Artery Aneurysms: Complications and Risk Factors for Complications. World Neurosurg. 2022 Dec;168:e87-e96. doi: 10.1016/j.wneu.2022.09.044. PMID: 36115562. https://www.sciencedirect.com/science/article/pii/S1878875022013213?via%3Dihub
  7. Burel J, Gerardin E, Vannier M, Curado A, Verdalle-Cazes M, Magne N, Lefebvre M, Papagiannaki C*. Follow-up of Intracranial Aneurysms Treated by Flow Diverters: Evaluation of Parent Artery Patency Using 3D-T1 Gradient Recalled-Echo Imaging with 2-Point Dixon in Combination with 3D-TOF-MRA with Compressed Sensing. AJNR Am J Neuroradiol. 2022. PMID: 35241422. https://www.ajnr.org/content/43/4/554.long
  8. Fontanilles M, Deniel A, Marguet F, Beaussire L, Magne N, Derrey S, Blanchard F, Alexandru C, Coutant S, Laquerrière A, Clatot F, Di Fiore F, Sarafan-Vasseur N. Usefulness of circulating tumor DNA from cerebrospinal fluid in recurrent high-grade glioma. Rev Neurol (Paris). 2022. PMID: 35871016. https://www.sciencedirect.com/science/article/pii/S0035378722006403?via%3Dihub
  9. Garnier L, Vidal C, Chinot O, Cohen-Jonathan Moyal E, Djelad A, Bronnimann C, Bekaert L, Taillandier L, Frenel JS, Langlois O, Colin P, Menei P, Dhermain F, Carpentier C, Gerazime A, Curtit E, Figarella-Branger D, Dehais C, Ducray F. Characteristics of Anaplastic Oligodendrogliomas Short-Term Survivors: A POLA Network Study. Oncologist. 2022 May 6;27(5):414-423. doi: 10.1093/oncolo/oyac023. PMID: 35522558. https://academic.oup.com/oncolo/article/27/5/414/6542926
  10. Montégut C, Guillamo JS, Ducray F, Dehais C, Cohen-Jonathan Moyal E, Desenclos C, Petit A, Seizeur R, Bekaert L, Gaultier C, Motuo Fotso MJ, Blonski M, Frenel JS, Vauléon E, Langlois O, Noel G, Carpentier AF, Di Stefano AL, Bronnimann C, Figarella-Branger D, Chinot O, Tabouret E. Characteristics, Patterns of Care and Predictive Geriatric Factors in Elderly Patients Treated for High-Grade IDH-Mutant Gliomas: A French POLA Network Study. Cancers (Basel). 2022 Nov 9;14(22):5509. doi: 10.3390/cancers14225509. PMID: 36428602. https://www.mdpi.com/2072-6694/14/22/5509
  11. Cheung G, Bataveljic D, Visser J, Kumar N, Moulard J, Dallérac G, Mozheiko D, Rollenhagen A, Ezan P, Mongin C, Chever O, Bemelmans AP, Lübke J, Leray I, Rouach N*. Physiological synaptic activity and recognition memory require astroglial glutamine. Nat Commun. 2022 Feb 8;13(1):753. doi: 10.1038/s41467-022-28331-7. PMID: 35136061. https://www.nature.com/articles/s41467-022-28331-7
  12. Sitsanidis ED, Kasapidou PM, Hiscock JR, Gubala V, Castel H, Popoola PIA, Hall AJ, Edwards AA. Probing the self-assembly and anti-glioblastoma efficacy of a cinnamoyl-capped dipeptide hydrogelator. Org Biomol Chem. 2022. PMID: 36094013. https://pubs.rsc.org/ob/article/20/37/7458/778759/Probing-the-self-assembly-and-anti-glioblastoma
  13. Brock S, Laquerriere A, Marguet F, Myers SJ, Hongjie Y, Baralle D, Vanderhasselt T, Stouffs K, Keymolen K, Kim S, Allen J, Shaulsky G, Chelly J, Marcorelle P, Aziza J, Villard L, Sacaze E, de Wit MCY, Wilke M, Mancini GMS, Hehr U, Lim D, Mansour S, Traynelis SF, Beneteau C, Denis-Musquer M, Jansen AC, Fry AE, Bahi-Buisson N*. Overlapping cortical malformations in patients with pathogenic variants in GRIN1 and GRIN2B. J Med Genet. 2023 Feb;60(2):183-192. doi: 10.1136/jmedgenet-2021-107971. PMID: 35393335. https://jmg.bmj.com/content/60/2/183.long
  14. Grangeon L, Roussel M, Gillibert A, Verdalle-Cazes M, Dolores M, Ozkul-Wermester O, Gilard V, Derrey S, Maltête D, Gerardin E, Joly LM, Wallon D, Magne N. Applicability of the Edinburgh CT Criteria for Lobar Intracerebral Hemorrhage Associated with Cerebral Amyloid Angiopathy. Clin Neuroradiol. 2023 Jun;33(2):455-465. doi: 10.1007/s00062-022-01230-6. PMID: 36598532. https://link.springer.com/article/10.1007/s00062-022-01230-6
  15. Picart T, Pallud J, Berthiller J, Dumot C, Berhouma M, Ducray F, Armoiry X, Margier J, Guerre P, Varlet P, Meyronet D, Metellus P, Guyotat J, et al.; RESECT study group. Use of 5-ALA fluorescence-guided surgery versus white-light conventional microsurgery for the resection of newly diagnosed glioblastomas (RESECT study): a French multicenter randomized phase III study. J Neurosurg. 2023. PMID: 37856381. https://thejns.org/view/journals/j-neurosurg/140/4/article-p987.xml
  16. Zhou T, Noeuveglise A, Modzelewski R, Ghazouani F, Thureau S, Fontanilles M, Ruan S*. Prediction of brain tumor recurrence location based on multi-modal fusion and nonlinear correlation learning. Comput Med Imaging Graph. 2023. PMID: 36947921. https://www.sciencedirect.com/science/article/pii/S0895611123000368?via%3Dihub
  17. Lacaud M, Leclerc A, Marguet F, Faisant M, Lesueur P, El Ouazzani H, Di Fiore F, Hanzen C, Emery E, Langlois O, Fontanilles M*. Impact of Covid-19 pandemic on neuro-oncology multidisciplinary tumor board in the pre-vaccine era: the Normandy experience. Neurochirurgie. 2023. PMID: 36870566. https://www.sciencedirect.com/science/article/pii/S0028377023000267?via%3Dihub
  18. Noeuveglise A, Sarafan-Vasseur N, Beaussire L, Marguet F, Modzelewski R, Hanzen C, Alexandru C, Magne N, Langlois O, Di Fiore F, Clatot F, Thureau S, Fontanilles M*. Impact of EGFRA289T/V mutation on relapse pattern in glioblastoma. ESMO Open. 2023. PMID: 36566697. https://www.esmoopen.com/article/S2059-7029(22)00374-X/fulltext
  19. Seyve A, Dehais C, Chinot O, Djelad A, Cohen-Moyal E, Bronnimann C, Gourmelon C, Emery E, Colin P, Boone M, Vauléon E, Langlois O, di Stefano AL, Seizeur R, Ghiringhelli F, D’Hombres A, Feuvret L, Guyotat J, Capelle L, Carpentier C, Garnier L, Honnorat J, Meyronet D, Mokhtari K, Figarella-Branger D, Ducray F*. Incidence and characteristics of pseudoprogression in IDH-mutant high-grade gliomas: A POLA network study. Neuro Oncol. 2023 Mar 14;25(3):495-507. doi: 10.1093/neuonc/noac194. PMID: 35953421. https://academic.oup.com/neuro-oncology/article/25/3/495/6661438?login=true
  20. Gernier F, Grellard JM, Dupont C, Castel H, Fernette M, Lahaye F, Charles RM, Leroux T, Ory C, Faveyrial A, Morel A, Emile G, Levy C, Segura C, Allouache D, Johnson A, Geffrelot J, Gunzer K, Lelaidier A, Girault G, Dubot-Poitelon C, San C, Lequesne J, Clarisse B. Impact of web application support versus standard management on adherence with adjuvant hormone therapy in patients treated for breast cancer: the WEBAPPAC study. BMC Cancer. 2023. PMID: 37559004. https://link.springer.com/article/10.1186/s12885-023-11242-1
  21. Cheung G, Chever O, Rollenhagen A, Quenech’du N, Ezan P, Lübke JHR, Rouach N*. Astroglial Connexin 43 Regulates Synaptic Vesicle Release at Hippocampal Synapses. Cells. 2023 Apr 11;12(8):1133. doi: 10.3390/cells12081133. PMID: 37190042. https://www.mdpi.com/2073-4409/12/8/1133
  22. Zavvar TS, Hörmann AA, Klingler M, Summer D, Rangger C, Desrues L, Castel H, Gandolfo P, von Guggenberg E. Effects of Side Chain and Peptide Bond Modifications on the Targeting Properties of Stabilized Minigastrin Analogs. Pharmaceuticals (Basel). 2023 Feb 13;16(2):278. doi: 10.3390/ph16020278. PMID: 37052226. https://www.mdpi.com/1424-8247/16/2/278
  23. Esparragosa Vazquez I, Sanson M, Chinot OL, Fontanilles M, Rivoirard R, Thomas-Maisonneuve L, Cartalat S, Tabouret E, Appay R, Bonneville-Levard A, Darlix A, Meyronet D, Barritault M, Gueyffier F, Remontet L, Maucort-Boulch D, Honnorat J, Dehais C, Ducray F; POLA Network. Olaparib in recurrent isocitrate dehydrogenase mutant high-grade glioma: A phase 2 multicenter study of the POLA Network. Neurooncol Adv. 2024. PMID: 38855053. https://academic.oup.com/noa/article/6/1/vdae078/7683070?login=true
  24. Daban A, Beaussire-Trouvay L, Lévêque É, Alexandru C, Tennevet I, Langlois O, Veresezan O, Marguet F, Clatot F, Di Fiore F, Sarafan-Vasseur N, Fontanilles M*. Prognostic value of circulating short-length DNA fragments in unresected glioblastoma patients. Transl Oncol. 2024 Apr;42:101897. doi: 10.1016/j.tranon.2024.101897. PMID: 38340682. https://www.sciencedirect.com/science/article/pii/S1936523324000238?via%3Dihub
  25. Dossi E, Zonca L, Pivonkova H, Milior G, Moulard J, Vargova L, Chever O, Holcman D, Rouach N*. Astroglial gap junctions strengthen hippocampal network activity by sustaining afterhyperpolarization via KCNQ channels. Cell Rep. 2024 May 28;43(5):114158. doi: 10.1016/j.celrep.2024.114158. PMID: 38722742. https://www.cell.com/cell-reports/fulltext/S2211-1247(24)00486-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124724004868%3Fshowall%3Dtrue
  26. Mayindza Ekaghba EL, Grenet M, Gandolfo P, Loutelier-Bourhis C, Schmitz I, Afonso C, Lerouge P, Mengome LE*. Phytochemical Analysis and Antidiarrheal Activity of Stem Bark Decoctions of Pentadesma butyracea Sabine (Clusiaceae). Molecules. 2024 Dec 7;29(23):5789. doi: 10.3390/molecules29235789. PMID: 39683945. https://www.mdpi.com/1420-3049/29/23/5789
  27. Yu Q, Shen X, Yi L, Liang M, Li G, Guan Z, Wu X, Castel H, Hu B, Yin P, Zhang W. Fragment-Fusion Transformer: Deep Learning-Based Discretization Method for Continuous Single-Cell Raman Spectral Analysis. ACS Sens. 2024 Aug 23;9(8):3907-3920. doi: 10.1021/acssensors.4c00149. PMID: 38934798. https://pubs.acs.org/ascefj/article/9/8/3907/144516/Fragment-Fusion-Transformer-Deep-Learning-Based
  28. Yi L, Zhang J, Wu J, Zhuang Y, Song Q, Zhao L, Liang M, Li G, Hu B, Yin P, Castel H, Maciuk A, Figadere B. Micro-macro SERS strategy for highly sensitive paper cartridge with trace-level molecular detection. Biosens Bioelectron. 2024 Nov 15;264:116665. doi: 10.1016/j.bios.2024.116665. PMID: 39173336. https://www.sciencedirect.com/science/article/pii/S0956566324006717?via%3Dihub
  29. Mayindza Ekaghba EL, Koumba Madingou NO, Grenet M, Gandolfo P, Perruchon O, Loutelier-Bourhis C, Schmitz I, Afonso C, Lerouge P, Mengome LE. Phytochemical Profile, Biological Activities and Potential Involvement of Opioid Receptors in Antinociceptive Effects of a Canarium schweinfurthii Engl. Int J Plant Anim Environ Sci. 2025. doi: 10.26502/ijpaes.4490177. (Sans PMID.) https://www.fortunejournals.com/articles/phytochemical-profile-biological-activities-and-potential-involvement-of-opioid-receptors-in-antinociceptive-effects-of-a-canarium.html
  30. Jaffres E, Dacher JN, Taalba M, Roca F, Garnier M, Normant S, Lozouet M, Gérardin E, Burel J. Possible limited justification for systematic head computed tomography scans based solely on antithrombotic therapy in elderly patients (aged 75 or older) with mild traumatic brain injury. Res Diagn Interv Imaging. 2025 Jan 16;13:100053. doi: 10.1016/j.redii.2024.100053. PMID: 39897447. https://www.sciencedirect.com/science/article/pii/S2772652524000140?via%3Dihub
  31. Marque T, Dumas V, Agripnidis T, Zhu F, Charbonnier G, Donnard B, Holay Q, Darcourt J, Scarcia L, Guédon A, L’Allinec V, Girot JB, Marnat G, Forestier G, Bellanger G, Alias Q, Bonnard L, Bourcier R, Allard J, Bretzner M, Coudert R, Rouchaud A, Hak JF, Lefebvre M, Gerardin E, Papagiannaki C, Burel J; JENI-Research Collaborative. Imaging follow-up of unruptured intracranial aneurysms treated with flow diverter: Insights from a French collaborative survey. J Neuroradiol. 2025 May;52(3):101338. doi: 10.1016/j.neurad.2025.101338. PMID: 40174673. https://www.sciencedirect.com/science/article/pii/S0150986125000963?via%3Dihub
  32. Patel A, Gerardin E, Poujol J, Dacher JN, Savoye-Collet C, Delpierre C, Wallon D, Chassagne P, Grangeon L, Burel J. Two-dimensional T2*-weighted multi-shot echo-planar imaging to detect cerebral microbleeds in neurocognitive disorders: A time-efficient alternative to susceptibility weighted angiography. Eur J Radiol. 2025 Feb;183:111915. doi: 10.1016/j.ejrad.2025.111915. PMID: 39764866. https://www.ejradiology.com/article/S0720-048X(25)00001-4/abstract
  33. Tauziède-Espariat A, Dangouloff-Ros V, Sievers P, Duchesne M, Siegfried A, Nicaise Y, Boddaert N, Hasty L, Métais A, Ngo C, le Loarer F, Bouvier C, Fontaine A, Rousseau A, Marguet F, Beccaria K, Blauwblomme T, Uro-Coste E, Varlet P; RENOCLIP-LOC. Glioneuronal tumors PATZ1-fused: clinico-molecular and DNA methylation signatures for a variety of morphological and radiological profiles. Acta Neuropathol Commun. 2025 May 24;13(1):114. doi: 10.1186/s40478-025-02037-5. PMID: 40413488. https://link.springer.com/article/10.1186/s40478-025-02037-5
  34. Stefan D, Lesueur P, Lequesne J, et al., Fontanilles M. Olaparib, Temozolomide, and Concomitant Radiotherapy for Partially Resected or Biopsy-Only Glioblastoma First-Line Treatment: OLA-TMZ-RTE-01 Phase I Study. Clin Cancer Res. 2025. PMID: 39882966. (liste d’auteurs complète non fournie dans le fichier source)
  35. Kacimi SEO, Dehais C, Feuvret L, Chinot O, Carpentier C, Bronnimann C, Vauleon E, Djelad A, Cohen-Jonathan Moyal E, Langlois O, Campone M, Ducloie M, Noel G, Cuzzubbo S, Taillandier L, Ramirez C, Younan N, Menei P, Dhermain F, Desenclos C, Ghiringhelli F, Bourg V, Ricard D, Faillot T, Appay R, Tabouret E, Nichelli L, Mathon B, Thomas A, Tran S, Bielle F, Alentorn A, Iorgulescu JB, Boëlle PY, Labreche K, Hoang-Xuan K, Sanson M, Idbaih A, Figarella-Branger D, Ducray F, Touat M; POLA Network. Survival Outcomes Associated With First-Line Procarbazine, CCNU, and Vincristine or Temozolomide in Combination With Radiotherapy in IDH-Mutant 1p/19q-Codeleted Grade 3 Oligodendroglioma. J Clin Oncol. 2025 Jan 20;43(3):329-338. doi: 10.1200/JCO.24.00049. PMID: 39356975.
  36. Bertucci A, Dufour O, Appay R, Harlay V, Ducray F, Bronnimann C, Djelad A, Cohen-Jonathan Moyal E, Campone M, Langlois O, Ducloie M, Vauleon E, Younan N, Desenclos C, Ramirez C, Touat M, Idbaih A, Bequet C, Figarella-Branger D, Dehais C, Chinot O, Tabouret E; POLA network. Characteristics, outcome, and prognostic factors of young patients with central nervous system World Health Organization grade 3 oligodendrogliomas IDH-mutant and 1p/19q codeleted: A French POLA network study. Cancer. 2025 Apr 1;131(7):e35814. doi: 10.1002/cncr.35814. PMID: 40159303. https://acsjournals.onlinelibrary.wiley.com/doi/10.1002/cncr.35814
  37. Pulcini S, Beaussire-Trouvay L, Marguet F, Viailly PJ, Langlois O, Alexandru C, Tennevet I, Di Fiore F, Sarafan-Vasseur N, Fontanilles M*. The clinical impact of EGFR alterations in elderly glioblastoma patients: results from a real-life cohort. J Neurooncol. 2025 Feb;171(3):619-628. doi: 10.1007/s11060-024-04879-w. PMID: 39549128. https://link.springer.com/article/10.1007/s11060-024-04879-w
  38. Lesueur P, Joly F, Clarisse B, Lequesne J, Stefan D, Balosso J, Lange M, Thureau S, Capel A, Castera M, Legrand B, Goliot N, Grellard JM, Tessonnier T, Castel H, Valable S. Correction: Neurocognitive impact of different irradiation modalities for patients with grade I-II skull base meningioma: a prospective multi-arm cohort study (CANCER COG). Radiat Oncol. 2025 Apr 29;20(1):67. doi: 10.1186/s13014-025-02650-7. PMID: 40301984. https://link.springer.com/article/10.1186/s13014-025-02650-7
  39. Lesueur P, Joly F, Clarisse B, Lequesne J, Stefan D, Balosso J, Lange M, Thureau S, Capel A, Castera M, Legrand B, Goliot N, Grellard JM, Tessonnier T, Castel H, Valable S. Neurocognitive impact of different irradiation modalities for patients with grade I-II skull base meningioma: a prospective multi-arm cohort study (CANCER COG). Radiat Oncol. 2025 Jan 29;20(1):16. doi: 10.1186/s13014-025-02591-1. PMID: 39881369. https://link.springer.com/article/10.1186/s13014-025-02591-1
  40. Duivon M, Christy F, Thomas E, Lequesne J, Castel H, Gaudin C, Delmas D, Boyault S, Rigal O, Bousrih C, Lévy C, Lerebours F, Di Meglio A, Ganz PA, Van Dyk K, Vaz Luis I, Lange M, Joly F. Interaction between APOE ε4 status, chemotherapy and endocrine therapy on cognitive functioning among breast cancer survivors: the CANTO-Cog longitudinal study. Breast Cancer Res. 2025 Feb 19;27(1):25. doi: 10.1186/s13058-025-01974-2. PMID: 39972319. https://link.springer.com/article/10.1186/s13058-025-01974-2
  41. Brunet L, Alexandre D, Lee J, Blanquer-Rosselló MDM, Bracquemond D, Guernet A, Chhouri H, Goupil M, Kherrouche Z, Arabo A, Mancini M, Cartier D, Yao S, Godefroy D, Dehedin J, Li JR, Duparc C, Jamme P, Vinchent A, Bérard C, Tulasne D, Arena S, Bardelli A, Cheng C, Cho BC, Wurtz O, Coulouarn C, Maraver A, Aaronson SA, Cortot AB, Anouar Y, Grumolato L. Prolonging lung cancer response to EGFR inhibition by targeting the selective advantage of resistant cells. Nat Commun. 2025 Aug 22;16(1):7853. doi: 10.1038/s41467-025-61788-w. PMID: 40846697. https://pmc.ncbi.nlm.nih.gov/articles/PMC12373916/
  42. Duplan E, Bernardin A, Goiran T, Leroudier N, Casimiro M, Pestell R, Tanaka S, Malleval C, Honnorat J, Idbaih A, Martin L, Castel H, Checler F, Alves da Costa C*. α-synuclein expression in glioblastoma restores tumor suppressor function and rescues temozolomide drug resistance. Cell Death Dis. 2025 Mar 19;16(1):188. doi: 10.1038/s41419-025-07509-z. PMID: 40108111. https://pmc.ncbi.nlm.nih.gov/articles/PMC11923286/
  43. Saracino D, Cipriano L, Houot M, Querin G, Rinaldi D, Rametti-Lacroux A, Wallon D, Gerardin E, Couratier P, Boncoeur MP, Lebouvier T; PREV-DEMALS and STRATALS study groups; Colliot O, Pradat PF, Migliaccio R, Le Ber I. Quantifying multimodal longitudinal brain changes in presymptomatic C9orf72 disease. Alzheimers Dement. 2025 Dec;21(12):e70902. doi: 10.1002/alz.70902. PMID: 41366786. https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.70902
  44. Vautier S, Levacher C, Marguet F, Kasper E, Sabourin JC, Baert-Desurmont S, Ruminy P, Houdayer C. Unraveling Circular and Messenger RNA Dynamics in Colorectal Tumorigenesis: Insights into Tissue Heterogeneity and MSI-MSS Tumor Distinction. Genes (Basel). 2026 Sep 10;17(9):1091. doi: 10.3390/genes17091091. PMID: 42792985. https://www.mdpi.com/2073-4425/17/9/1091
  45. Zunino C, Rabaux E, Marguet F, Mafrici M, Muraine M, Lorenzi U. Hemorrhagic retinal cysts revealing astrocytic glial hyperplasia 20 years after vitrectomy for post-traumatic retinal detachment. Eur J Ophthalmol. 2026 May;36(3):761-766. doi: 10.1177/11206721251407374. PMID: 41442248. https://journals.sagepub.com/doi/10.1177/11206721251407374?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed  
  46. Merlette M, Rouchaud A, Mounayer C, Shotar E, Papagiannaki C, Couquet C, Forestier G, Crampon F, Garrido E, Gerardin E, Clarençon F, Burel J. Practical arterial atlas of the pig for neurointerventional simulation. J Neurointerv Surg. 2026 Aug 17;18(9):1940-1947. doi: 10.1136/jnis-2025-024149. PMID: 41047221. https://jnis.bmj.com/content/18/9/1940.long
  47. Beaufort Q, Charbonnier C, Ruellan P, Ozkul-Wermester O, Amar V, Turpin D, Quillard-Muraine M, Gerardin E, Dufour D, Charidimou A, Balageas AC, Boulouis G, Pasi M, Wallon D, Grangeon L. Evaluation of Disease Severity Using CSF Biomarkers in Patients With Probable Cerebral Amyloid Angiopathy. Neurology. 2026 Sep 22;107(6):e218458. doi: 10.1212/WNL.0000000000218458. PMID: 42691466. https://www.neurology.org/doi/10.1212/WNL.0000000000218458?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed  

Reviews, book chapters, conference proceedings and guidelines

  1. Piton N, Marguet F, Guisier F, Lamy A, Sabourin JC*. Le RNAseq en oncologie de routine [RNAseq in routine oncology]. Ann Pathol. 2021 Sep;41(5):463-469. doi: 10.1016/j.annpat.2021.06.003. PMID: 34376297. https://www.sciencedirect.com/science/article/pii/S024264982100136X?via%3Dihub
  2. Klionsky DJ et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 2021. PMID: 33634751. (Publication internationale à très nombreux auteurs.) https://www.tandfonline.com/doi/10.1080/15548627.2020.1797280?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
  3. Cohen-Salmon M, Slaoui L, Mazaré N, Gilbert A, Oudart M, Alvear-Perez R, Elorza-Vidal X, Chever O, Boulay AC*. Astrocytes in the regulation of cerebrovascular functions. Glia. 2021 Apr;69(4):817-841. doi: 10.1002/glia.23924. PMID: 33058289. https://onlinelibrary.wiley.com/doi/10.1002/glia.23924
  4. Chinigò G, Castel H, Chever O, Gkika D*. TRP Channels in Brain Tumors. Front Cell Dev Biol. 2021 Apr 13;9:617801. doi: 10.3389/fcell.2021.617801. PMID: 33928077. https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2021.617801/full
  5. Clavreul A, Autier L, Lemée JM, Augereau P, Soulard G, Bauchet L, Figarella-Branger D, Menei P, Network F; Collaborators of the FGB network. Management of Recurrent Glioblastomas: What Can We Learn from the French Glioblastoma Biobank? Cancers (Basel). 2022 Nov 9;14(22):5510. doi: 10.3390/cancers14225510. PMID: 36428604. https://www.mdpi.com/2072-6694/14/22/5510
  6. Tarhan MC, Mutel A, Desrues L, Collard D, Castel H*. Glioblastoma migration along constraints with different geometries: how to mimic brain parenchyma invasion? 2022 IEEE 35th International Conference on Micro Electro Mechanical Systems (MEMS).
  7. Hilber P*. The Role of the Cerebellar and Vestibular Networks in Anxiety Disorders and Depression: the Internal Model Hypothesis. Cerebellum. 2022 Oct;21(5):791-800. doi: 10.1007/s12311-022-01400-9. PMID: 35414040. https://link.springer.com/article/10.1007/s12311-022-01400-9
  8. European Cancer and Cognition Consortium (ECCC)* Sleurs C, Amidi A, Wu LM, Kiesl D, Zimmer P, Lange M, Rogiers A, Giffard B, Binarelli G, Borghgraef C, Deprez S, Duivon M, De Ruiter M, Schagen S, Ahmed-Lecheheb D, Castel H*, Buskbjerg CR, Dos Santos M, Joly F, Perrier J. Cancer-related cognitive impairment in non-CNS cancer patients: Targeted review and future action plans in Europe. Crit Rev Oncol Hematol. 2022 Dec;180:103859. doi: 10.1016/j.critrevonc.2022.103859. PMID: 36257539. https://www.sciencedirect.com/science/article/pii/S1040842822002839?via%3Dihub
  9. Campisi D, Desrues L, Dembélé KP, Mutel A, Parment R, Gandolfo P, Castel H, Morin F*. Chemotactic cell migration: the core autophagy protein ATG9A is at the leading edge. Autophagy. 2022 Dec;18(12):3037-3039. doi: 10.1080/15548627.2022.2069903. PMID: 35468023. https://www.tandfonline.com/doi/10.1080/15548627.2022.2069903?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
  10. Bikfalvi A, da Costa CA, Avril T, et al. Erratum: Challenges in glioblastoma research: focus on the tumor microenvironment. Trends Cancer. 2023 Aug;9(8):692. doi: 10.1016/j.trecan.2023.02.006. PMID: 36997420. https://www.cell.com/trends/cancer/fulltext/S2405-8033(23)00029-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2405803323000298%3Fshowall%3Dtrue
  11. Bikfalvi A, da Costa CA, Avril T, Barnier JV, Bauchet L, Brisson L, Cartron PF, Castel H, Chevet E, Chneiweiss H, Clavreul A, Constantin B, Coronas V, Daubon T, Dontenwill M, Ducray F, Entz-Werlé N, Figarella-Branger D, Fournier I, Frenel JS, Gabut M, Galli T, Gavard J, Huberfeld G, Hugnot JP, Idbaih A, Junier MP, Mathivet T, Menei P, Meyronet D, Mirjolet C, Morin F, Mosser J, Moyal EC, Rousseau V, Salzet M, Sanson M, Seano G, Tabouret E, Tchoghandjian A, Turchi L, Vallette FM, Vats S, Verreault M, Virolle T. Challenges in glioblastoma research: focus on the tumor microenvironment. Trends Cancer. 2023 Jan;9(1):9-27. doi: 10.1016/j.trecan.2022.09.005. PMID: 36400694. https://www.cell.com/trends/cancer/abstract/S2405-8033(22)00220-5?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2405803322002205%3Fshowall%3Dtrue
  12. Roy Choudhury N, Hilber P, Cendelin J. Lurcher Mouse as a Model of Cerebellar Syndromes. Cerebellum. 2025 Feb 28;24(2):54. doi: 10.1007/s12311-025-01810-5. PMID: 40016581. https://link.springer.com/article/10.1007/s12311-025-01810-5
  13. Joly F, Castel H, Compter A, Nicola C, Duivon M, Lange M. Neuropsychological and central neurologic effects of cancer immunotherapy: the start of a new challenge. J Clin Exp Neuropsychol. 2025 Oct;47(8):768-787. doi: 10.1080/13803395.2025.2498713. PMID: 40323211.
  14. Kuil LE, Nicola C, Dietrich J, Castel H*. Neurotoxicity of chemotherapy and brain-radiotherapy in cancer: overlapping mechanisms underlying cognitive impairment. J Clin Exp Neuropsychol. 2025 Oct;47(8):806-846. doi: 10.1080/13803395.2025.2539199. PMID: 40784023.
  15. Martin L*, Cochois C*, Moreno-Sanchez PM*, Oudin A, Busek P, Oliynyk I, Gobbo O, Geyik ÖG, Akar RO, Ulukaya E, Topal T, Caillot M, Tchoghandjian A, Breznik B, Laurenzana A, Danielyan K, Barberá VM, de Juan Romero C, Dietis N, Tunca B, Ercelik M, Tekin C, Caetano Oliveira R, Connor K, Sosnik A, Bagci Onder T, Sarac Yalcinkaya S, Taleban H, Ramos S, Jurisch-Yaksi N, Acar A, Altendorfer-Kroath T; NET4BRAIN EU COST Action WG2, Golebiewska A, Castel H*. In vivo preclinical models of brain tumors: Choosing the right model for the right question. Front Immunol, In revision.
  16. Hilber P*. Mental Models of the Cerebellum. In: Encyclopedic Dictionary of the Cerebellum. Springer Nature; 2026.
  17. Carmon A, Hilber P, Castel H, Dubois M*. Examination of Behavior, Cognition, and Motor Function in Rodents and Alternative Models. In: Cendelín J, Tuma J, Manto M, editors. Models of Neurodegenerative Diseases. Springer Nature, Cham; 2026. pp. 277-310. doi: 10.1007/978-3-032-18296-8_9. https://link.springer.com/chapter/10.1007/978-3-032-18296-8_9
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